ALESSANDRA GONÇALVES COMMODARO

 

Alessandra Gonçalves Commodaro
E.mail: commodaro.alessandra@nih.gov
Home Address: 
4550 Connecticut Ave, Washington, DC

 

EDUCATION:
1995 BS, Speech Therapist, Sao Camilo University, Sao Paulo, Brasil

2001 MS, Science, Anatomy Department, University of Sao Paulo, Brasil

2005 Ph.D., Science, Immunology Department, University of Sao Paulo, Brasil

April 2007 – 2010, Post Doctoral, Department of Ophthalmology, Federal University of Sao Paulo, Brasil.

2010 – Present, Post Doctoral, Laboratory of Parasitic Diseases, NIAID, NIH

Honors and Awards
2009 – ARVO International Travel Grant, ARVO Annual Meeting 2009

2010 – CAPES Fellowship, for Postdoctoral Research at National Institutes of Health

OTHER PROFISSIONAL ACTIVITIES:
– March 2012 – Organization of the Workshop “Population Biology and detection of Toxoplasma infection” – SIMASP 2012, UNIFESP/ Sao Paulo, Brazil

PUBLICATIONS IN PEER REVIEWED JOURNALS:
1. Martín AP, de Moraes LV, Tadokoro CE, Commodaro AG, Urrets-Zavalia E, Rabinovich GA, Urrets-Zavalia J, Rizzo LV, Serra HM. Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2005 Jun;46(6):2056-63.

 

2. Toscano MA*, Commodaro AG*, Ilarregui JM, Bianco GA, Liberman A, Serra HM, Hirabayashi J, Rizzo LV, Rabinovich GA. Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses. J Immunol. 2006 May 15;176(10):6323-32. NOTE: *Equal contribution.

 

3. Vallochi AL, Commodaro AG, Schwartzman JP, Belfort R Jr, Rizzo LV. The role of cytokines in the regulation of ocular autoimmune inflammation. Cytokine Growth Factor Rev. 2007 Feb-Apr;18(1-2):135-41. Review.

 

4. Figueiredo F, Commodaro AG, de Camargo MM, Rizzo LV, Belfort R Jr. NK1.1 cells downregulate murine endotoxin-induced uveitis following intraocular administration of interleukin-12. Scand J Immunol. 2007 Aug-Sep;66(2-3):329-34.

 

5. Alessandra G Commodaro, Rubens N Belfort, Luiz Vicente Rizzo, Cristina Muccioli, Claudio Silveira, Miguel N Burnier Jr, Rubens Belfort Jr. Ocular toxoplasmosis – an update and review of the literature. Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 104(2): 345-350, 2009

 

6. Marengo EB*, Commodaro AG*, Peron JP, de Moraes LV, Portaro FC, Belfort R Jr, Rizzo LV, Sant’Anna OA. Administration of Mycobacterium leprae rHsp65 aggravates experimental autoimmune uveitis in mice. PLoS One. 2009 Nov 19;4(11). NOTE: *Equal contribution.

 

7. Commodaro AG, Peron JP, Lopes CT, Arslanian C, Belfort R Jr, Rizzo LV, Bueno V. Evaluation of experimental autoimmune uveitis in mice treated with FTY720. Invest Ophthalmol Vis Sci. 2010 May;51(5):2568-74.

 

8. Commodaro AG, Bombardieri CR, Peron JP, Saito KC, Guedes PM, Hamassaki DE, Belfort RN, Rizzo LV, Belfort R Jr, de Camargo MM. p38{alpha} MAP kinase controls IL-17 synthesis in vogt-koyanagi-harada syndrome and experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3567-74.

 

9. Commodaro AG, Peron JP, Genre J, Arslanian C, Sanches L, Muccioli C, Rizzo LV, Belfort R Jr. IL-10 and TGF-beta immunoregulatory cytokines rather than natural regulatory T cells are associated with the resolution phase of Vogt-Koyanagi-Harada (VKH) syndrome. Scand J Immunol. 2010 Jul;72(1):31-7.

10. Peron JP, Yang K, Chen ML, Brandao WN, Basso AS, Commodaro AG, Weiner HL, Rizzo LV. Oral tolerance reduces Th17 cells as well as the overall inflammation in the central nervous system of EAE mice. J Neuroimmunol. 2010 Oct 8;227(1-2):10-7.

 

11. Commodaro, Alessandra Gonçalves; Moraes, Luciana de Deus Vieira de; Tambourgi, Denise Vilarinho; Belfort Jr, Rubens; SantAnna, Osvaldo Augusto; Rizzo, Luiz Vicente. Autoimmune uveitis: study of treatment therapies / Uveíte autoimune: estudo de terapias para tratamento. Einstein (Säo Paulo);8(1), jan.-mar. 2010. Id: 542640.

 

12. Commodaro AG, Bueno V, Belfort R Jr, Rizzo LV.Autoimmune uveitis: The associated proinflammatory molecules and the search for immunoregulation.Autoimmun Rev. 2010 Oct 17.

 

13. Santos FF, Commodaro AG, Souza AV, Pinho JR, Sitnik R, Garcia C, Ribeiro AL, Muccioli C, Lottenberg CL, Rizzo LV, Belfort Junior R.. Real-time PCR in infectious uveitis as an alternative diagnosis. Arq Bras Oftalmol. 2011 Aug;74(4):258-61.

 

14. Alessandra Goncalves Commodaro, Juliana Figueredo Pedregosa Jean Pierre Peron, Wesley Branda˜o, Luiz Vicente Rizzo, Valquiria Bueno. The imbalance between Treg and Th17 cells caused by FTY720 treatment in skin allograft rejection. CLINICS 2012;67(7):805-813.

 

15 Alessandra Gonçalves Commodaro, Eliana Blini Marengo, Jean Pierrw Schatzmann Peron, Wesley Brandao, Cristina Arslanian, Robson L. Melo, Estevam José Baldon, Rubens Belfort Jr., Osvaldo Augusto Sant’Anna and Luiz Rizzo. The Role of M. Leprae Hsp65 Protein and Peptides in The Pathogenesis of Uveitis Aceito para publicacao no Autoimmune Diseases. Article 197648.